Tretinoin Powder

Tretinoin Powder

Our product all come from nature.We are amp factory.Clean workshop production. They have high purity and solubility.Our price is favorable.Timely and efficient transport.Support various payment methods.Minimum order quantity 1 kg.Free proofing.We have our own factories.We offer free samples.We have focused on this field over 10 years.

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Product Details

1-product details

1. Product name: Tretinoin

2. Active ingredient: Tretinoin

3. CAS NO.: 302-79-4

4. Molecular formula: C20H28O2

5. Molecular Weight: 300.44

6. Characters: white powder with slight yellow cast

7. Usage: Pharmaceuticals, healthcares,and cosmetics

2-product description

Successfully treating acute promyelocytic leukemia (APL) with Tretinoin was a major breakthrough in APL therapy. It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor (RAR) gene to the promyelocytic leukemia (PML) gene.This fusion PML-RAR protein is responsible for preventing immature myeloid cells from differentiating into more mature cells. This block in differentiation is thought to cause leukemia. ATRA acts on PML-RAR to lift this block, causing the immature promyelocytes to differentiate to normal mature blood cells thus decreasing promyelocytes.  

3-product analysis

Item

  Specification

  Result

  Method

BasicProduct Information

Product name

tretinoin powder



Part of the Plant

body

Conform

/

Country of Origin

China

Conform

/

Organoleptic Data

Appearance

Fine powder

Conform

NLS-QCS-1008

Color

white powder with slight yellow cast

Conform

GB/T 5492-2008

Odor& Taste

Characteristic

Conform

GB/T 5492-2008

Process Data

Solvent(s) Used

Water and ethyl alcohol

Conform

/

Extract ration

/

Conform


Content

Paeoniflorin98%

98.17


Drying Method

Spray drying

Conform

/

Excipient

Maltodextrin 

Conform

/

Physical Characteristics

Particle Size (80 mesh)

98.0%pass 80mesh

Conform

GB/T 5507-2008

Moisture

<5.0%

2.7%

GB/T 14769-1993

Ash Content

<4.0%

1.3%

AOAC 942.05, 18th

Solvent Residue

Eur. Pharm

Conform

NLS-QCS-1007

Heavy Metals

Total Heavy Metals

<10 ppm

Conform

USP <231>, method II

Arsenic

<1.0 ppm

Conform

AOAC 986.15, 18th

Lead

<1.0 ppm

Conform

AOAC 986.15, 18th

Mercury

<0.5 ppm

Conform

AOAC 971.21, 18th

Pesticide Residue

666

<0.2ppm

Conform

GB/T5009.19-1996

DDT

<0.2ppm

Conform

GB/T5009.19-1996

Microbiology

Total Plate Count

<1,000cfu/g

16cfu/g

AOAC 990.12, 18th

Total Yeast & Mold

<100cfu/g

2cfu/g

FDA (BAM) Chapter 18, 8th Ed.

E. Coli

Negative

Negative

AOAC 997.11, 18th

Salmonella

Negative

Negative

FDA (BAM) Chapter 5, 8th Ed.

tretinoin powder

If you are interested in our product, PLS no hesitate to contact us. We will supply superior quality product and excellent service for you.  https://www.bgherbalextract.com/contact-us

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