Tetrandrine

Tetrandrine

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Product Details

1-product details

Product name:Corydalis Extract

Extract source:Stephania tetrandra S.Moore

Specification:98%

Active ingredient:Tetrandrine

Used Part:Root

CAS NO. : 518-34-3

Molecular formula :C38H42N2O6

Molecular weight:622.75

Appearance:White powder

Flavor: Characteristic taste

Particle Size:80% pass through 80 mesh sieve

Test mothed: HPLC

Extract Solvent: Ethanol & Water

Solubility:Hardly soluble in water and easily in aether

Usage: Pharmaceuticals, healthcares,and cosmetics

2-product description

Tetrandrine a bis-benzylisoquinoline alkaloid, is a calcium channel blocker. It has anti-inflammatory, immunologic and antiallergenic effects. It inhibits the degranulation of mast cells. It has a "Quinidine like" anti-arrhythmic effect. It has been isolated from Stephania tetrandra S Moore,and other Chinese and Japanese herbs. It has vasodilatory properties and can therefore reduce blood pressure. Tetrandrine may have potential use for the treatment of liver disease and liver cancer. Tetrandrine has potential therapeutic value to prevent excess scarring/fibrosis in conjunctiva following trabeculectomy or in patients with severe conjunctival inflammation.Tetrandrine has anti-inflammatory and anti-fibrogenic actions, which make tetrandrine and related compounds potentially useful in the treatment of lung silicosis, liver cirrhosis, and rheumatoid arthritis.

3-product analysis

Item

  Specification

  Result

  Method

BasicProduct Information

Product name

tetrandrine



Part of the Plant

Whole plant

Conform

/

Country of Origin

China

Conform

/

Organoleptic Data

Appearance

Fine powder

Conform

NLS-QCS-1008

Color

white powder

Conform

GB/T 5492-2008

Odor& Taste

Characteristic

Conform

GB/T 5492-2008

Process Data

Solvent(s) Used

Water and ethyl alcohol

Conform

/

Extract ration

/

Conform


Content

Paeoniflorin98%

98.16


Drying Method

Spray drying

Conform

/

Excipient

Maltodextrin 

Conform

/

Physical Characteristics

Particle Size (80 mesh)

98.0%pass 80mesh

Conform

GB/T 5507-2008

Moisture

<5.0%

2.6%

GB/T 14769-1993

Ash Content

<4.0%

1.1%

AOAC 942.05, 18th

Solvent Residue

Eur. Pharm

Conform

NLS-QCS-1007

Heavy Metals

Total Heavy Metals

<10 ppm

Conform

USP <231>, method II

Arsenic

<1.0 ppm

Conform

AOAC 986.15, 18th

Lead

<1.0 ppm

Conform

AOAC 986.15, 18th

Mercury

<0.5 ppm

Conform

AOAC 971.21, 18th

Pesticide Residue

666

<0.2ppm

Conform

GB/T5009.19-1996

DDT

<0.2ppm

Conform

GB/T5009.19-1996

Microbiology

Total Plate Count

<1,000cfu/g

15cfu/g

AOAC 990.12, 18th

Total Yeast & Mold

<100cfu/g

5cfu/g

FDA (BAM) Chapter 18, 8th Ed.

E. Coli

Negative

Negative

AOAC 997.11, 18th

Salmonella

Negative

Negative

FDA (BAM) Chapter 5, 8th Ed.

4-product function

1. Anti-allergic effects
2. The role of anti-angina
3.Anti-tumor effect, tetrandrine hormone is an effective adjuvant treatment of cancer
4.Antihypertensive effect, Some other clinical observations that tetrandrine the antihypertensive effect of significant factors

5.In addition, tetrandrine factors for leukemia, nerve pain, heart disorders and other diseases have a better therapeutic effect

01

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