Rotundine

Rotundine

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Product Details

1-product details

Product name: Rotundine

Synonym:tetrahydropalmatine;5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-6h-dibenzo[a,g] quinolizine

Plant source: Stephania epigaea H. S. Lo

Specification:98%

Active ingredient:Rotundine

CAS NO. : 10097-84-4

Molecular formula :C21H25NO4

Molecular weight:355.43

Appearance: White powder

Flavor: Characteristic taste

Particle Size:80% pass through 80 mesh sieve

Test mothed: HPLC

Melting Point: 141-144 ºC

Specific rotation (25 ºC): -290 to -300°

Extract Solvent: Ethanol & Water

Solubility: Dissolved in chloroform, ethanol or ether in slightly soluble, insoluble in water; soluble in dilute sulfuric acid.

Usage: Pharmaceuticals, healthcares,and cosmetics

2-product description

Rotundine is an active alkaloid isolated from the stem tubers of the Chinese medicinal herb Corydalis sp. It is the l-optical isomer of tetrahydropalmatine.Rotundin is mainly used in  acesodyne: pain for visceral pain caused by digestive diseases (such as gastric ulcer and duodenal  ulcer pain ) , general headache , menstrual pian , pian after childbirth constractions . Also, Sedative and hypnotic : for tension caused by pain or insomnia due to pain patients 

3-product analysis

Item

  Specification

  Result

  Method

BasicProduct Information

Product name

rotundine



Part of the Plant

Stem&tuber

Conform

/

Country of Origin

China

Conform

/

Organoleptic Data

Appearance

Fine powder

Conform

NLS-QCS-1008

Color

white powder

Conform

GB/T 5492-2008

Odor& Taste

Characteristic

Conform

GB/T 5492-2008

Process Data

Solvent(s) Used

Water and ethyl alcohol

Conform

/

Extract ration

/

Conform


Content

Paeoniflorin98%

98.16


Drying Method

Spray drying

Conform

/

Excipient

Maltodextrin 

Conform

/

Physical Characteristics

Particle Size (80 mesh)

98.0%pass 80mesh

Conform

GB/T 5507-2008

Moisture

<5.0%

2.9%

GB/T 14769-1993

Ash Content

<4.0%

1.3%

AOAC 942.05, 18th

Solvent Residue

Eur. Pharm

Conform

NLS-QCS-1007

Heavy Metals

Total Heavy Metals

<10 ppm

Conform

USP <231>, method II

Arsenic

<1.0 ppm

Conform

AOAC 986.15, 18th

Lead

<1.0 ppm

Conform

AOAC 986.15, 18th

Mercury

<0.5 ppm

Conform

AOAC 971.21, 18th

Pesticide Residue

666

<0.2ppm

Conform

GB/T5009.19-1996

DDT

<0.2ppm

Conform

GB/T5009.19-1996

Microbiology

Total Plate Count

<1,000cfu/g

13cfu/g

AOAC 990.12, 18th

Total Yeast & Mold

<100cfu/g

4cfu/g

FDA (BAM) Chapter 18, 8th Ed.

E. Coli

Negative

Negative

AOAC 997.11, 18th

Salmonella

Negative

Negative

FDA (BAM) Chapter 5, 8th Ed.

4-product function

1.It has effect of promoting blood circulation to remove blood stasis and promoting circulation of qi to relieve pain,
2.It is often used for hypochondriac pain due to stagnation of the liver-qi, stomachache due to stagnation of the stomach-qi, hernial pain.

C4A5CC951906F17F10E4BB814E7F0EE3

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