Podophyllotoxin Tincture

Podophyllotoxin Tincture

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Product Details

1-product details

Product name: Podophyllum Extract

Latin Name:Podophyllotoxin Tincture

Specification:98%

Active ingredient: Podophyllotoxin

CAS No.518-28-5

Molecular formular: C22H22O8

Molecular weight: 414.40

Appearance: white powder

Flavor: Characteristic taste

Particle Size:80% pass through 80 mesh sieve

Test mothed: HPLC

Extract Solvent: Ethanol & Water

Usage: Pharmaceuticals, healthcares,and cosmetics

2-product description

Podophyllotoxin (abbreviated as PPT), otherwise known as podofilox, is a non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species. Under the trade name Condylox, a topical gel, it is used on the skin to treat external genital warts, caused by some types of the human papillomavirus (HPV). Under the trade name Wartec solution, it is used on the skin to treat external genital warts and other warts. PPT and its derivatives display a wide selection in medical applications such as purgative, vesicant, antirheumatic, antiviral, and antitumor agents. These derivatives include etoposide, teniposide, and etopophos. Their anticancer activity has been heavily under study and used in various chemotherapies, including lung cancer, lymphomas, and genital tumors.

3-product analysis

Item

  Specification

  Result

  Method

BasicProduct Information

Product name

podophyllotoxin tincture



Part of the Plant

Root&rhizome

Conform

/

Country of Origin

China

Conform

/

Organoleptic Data

Appearance

Fine powder

Conform

NLS-QCS-1008

Color

white powder

Conform

GB/T 5492-2008

Odor& Taste

Characteristic

Conform

GB/T 5492-2008

Process Data

Solvent(s) Used

Water and ethyl alcohol

Conform

/

Extract ration

/

Conform


Content

Paeoniflorin98%

98.20


Drying Method

Spray drying

Conform

/

Excipient

Maltodextrin 

Conform

/

Physical Characteristics

Particle Size (80 mesh)

98.0%pass 80mesh

Conform

GB/T 5507-2008

Moisture

<5.0%

2.5%

GB/T 14769-1993

Ash Content

<4.0%

1.5%

AOAC 942.05, 18th

Solvent Residue

Eur. Pharm

Conform

NLS-QCS-1007

Heavy Metals

Total Heavy Metals

<10 ppm

Conform

USP <231>, method II

Arsenic

<1.0 ppm

Conform

AOAC 986.15, 18th

Lead

<1.0 ppm

Conform

AOAC 986.15, 18th

Mercury

<0.5 ppm

Conform

AOAC 971.21, 18th

Pesticide Residue

666

<0.2ppm

Conform

GB/T5009.19-1996

DDT

<0.2ppm

Conform

GB/T5009.19-1996

Microbiology

Total Plate Count

<1,000cfu/g

16cfu/g

AOAC 990.12, 18th

Total Yeast & Mold

<100cfu/g

5cfu/g

FDA (BAM) Chapter 18, 8th Ed.

E. Coli

Negative

Negative

AOAC 997.11, 18th

Salmonella

Negative

Negative

FDA (BAM) Chapter 5, 8th Ed.

4-product function

1.Anthelmintic to treat parasitic worm infections

2.Treat deafness

3.Treat snake bites

4.As a purgative and laxative

5.As a suicidal potion

05

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