Fructus Xanthii

Fructus Xanthii

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Product Details

1-product details

1. Product name: Siberian Cocklebur Fruit Extract

2. Botanical source: Xanthium sibiricum Patr.

3. Biogenic origin: Wild in central and southern China

4. Specification: 10:1

5. Characters: Brown powder

6. Usage: Pharmaceuticals, healthcares,and cosmetics

2-product description

Siberian cocklebur is an annual spring weed long used in Traditional Chinese medicine (TCM). It grows mainly in northern Iran, Siberia, China, Japan, and other parts of central Asia. Siberian cocklebur belongs to the Asteraceae family. Its flavor has been described as pungent. The herb has an acrid and sweet taste.

Siberian cocklebur contains the toxic glucosides, atractyloside and carboxyastractyloside. Based on secondary sources, these toxic compounds may target tissues and organs of high metabolic activity and cause a severe hepatitis with fatal liver failure. Also, these compounds may interact with detoxification or transformation systems in the liver at doses not thought to induce cytolysis. It has been suggested that this is due to blocking ADP-to-ATP conversion through inhibition of cytochrome P450. Clinical manifestations may be related to induced hypoglycemia, neurovegetative disorders, or subsequent renal failure.

3-product analysis

Item

  Specification

  Result

  Method

BasicProduct Information

Product name

fructus xanthii



Part of the Plant

fruit

Conform

/

Country of Origin

China

Conform

/

Organoleptic Data

Appearance

Fine powder

Conform

NLS-QCS-1008

Color

Brown powder

Conform

GB/T 5492-2008

Odor& Taste

Characteristic

Conform

GB/T 5492-2008

Process Data

Solvent(s) Used

Water and ethyl alcohol

Conform

/

Extract ration

/

Conform


Content

Paeoniflorin98%

98.22


Drying Method

Spray drying

Conform

/

Excipient

Maltodextrin 

Conform

/

Physical Characteristics

Particle Size (80 mesh)

98.0%pass 80mesh

Conform

GB/T 5507-2008

Moisture

<5.0%

3.2%

GB/T 14769-1993

Ash Content

<4.0%

1.8%

AOAC 942.05, 18th

Solvent Residue

Eur. Pharm

Conform

NLS-QCS-1007

Heavy Metals

Total Heavy Metals

<10 ppm

Conform

USP <231>, method II

Arsenic

<1.0 ppm

Conform

AOAC 986.15, 18th

Lead

<1.0 ppm

Conform

AOAC 986.15, 18th

Mercury

<0.5 ppm

Conform

AOAC 971.21, 18th

Pesticide Residue

666

<0.2ppm

Conform

GB/T5009.19-1996

DDT

<0.2ppm

Conform

GB/T5009.19-1996

Microbiology

Total Plate Count

<1,000cfu/g

21cfu/g

AOAC 990.12, 18th

Total Yeast & Mold

<100cfu/g

7cfu/g

FDA (BAM) Chapter 18, 8th Ed.

E. Coli

Negative

Negative

AOAC 997.11, 18th

Salmonella

Negative

Negative

FDA (BAM) Chapter 5, 8th Ed.

fructus xanthii

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