Bergeninum 477-90-7

Bergeninum 477-90-7

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Product Details

1-product details

Product name:Bergenia purpurascens Extract

Herb Source: Bergenia purpurascens engl.

Plant extract Orginal: Bergenia purpurascens, B.crassifoloa,Astilbe macroflora, Ardisia crispa.

Specification:98%

Active ingredient:Bergenin

Used Part:Leaf

CAS NO. : 477-90-7

Molecular formula :C14H16O9

Molecular weight:328.28

Appearance:White crystal powder

Flavor: Characteristic taste

Particle Size:80% pass through 80 mesh sieve

Test mothed: HPLC

Extract Solvent: Ethanol & Water

Usage: Pharmaceuticals, healthcares,and cosmetics

2-product description

Bergenin alias Cuscutin is trihydroxybenzoic acid glycoside. It is the C-glycoside of 4-O-methyl gallic acid. It possesses an O-demethylated derivative called norbergenin. These are chemical compounds and drugs of Ayurveda, commonly known as Paashaanbhed. It shows a potent immunomodulatory effect.

Bergenin can be isolated from Bergenia species like Bergenia ciliata and Bergenia ligulata,[2] from rhizomes of Bergenia stracheyi. It is also found in the stem bark of Dryobalanops aromatica,[3] in Ardisia elliptica and in Mallotus japonicus

3-product analysis

Item

  Specification

  Result

  Method

BasicProduct Information

Product name

bergeninum 477-90-7



Part of the Plant

leaf

Conform

/

Country of Origin

China

Conform

/

Organoleptic Data

Appearance

Fine powder

Conform

NLS-QCS-1008

Color

White crystal powder

Conform

GB/T 5492-2008

Odor& Taste

Characteristic

Conform

GB/T 5492-2008

Process Data

Solvent(s) Used

Water and ethyl alcohol

Conform

/

Extract ration

/

Conform


Content

Paeoniflorin98%

98.17


Drying Method

Spray drying

Conform

/

Excipient

Maltodextrin 

Conform

/

Physical Characteristics

Particle Size (80 mesh)

98.0%pass 80mesh

Conform

GB/T 5507-2008

Moisture

<5.0%

2.9%

GB/T 14769-1993

Ash Content

<4.0%

1.5%

AOAC 942.05, 18th

Solvent Residue

Eur. Pharm

Conform

NLS-QCS-1007

Heavy Metals

Total Heavy Metals

<10 ppm

Conform

USP <231>, method II

Arsenic

<1.0 ppm

Conform

AOAC 986.15, 18th

Lead

<1.0 ppm

Conform

AOAC 986.15, 18th

Mercury

<0.5 ppm

Conform

AOAC 971.21, 18th

Pesticide Residue

666

<0.2ppm

Conform

GB/T5009.19-1996

DDT

<0.2ppm

Conform

GB/T5009.19-1996

Microbiology

Total Plate Count

<1,000cfu/g

18cfu/g

AOAC 990.12, 18th

Total Yeast & Mold

<100cfu/g

4cfu/g

FDA (BAM) Chapter 18, 8th Ed.

E. Coli

Negative

Negative

AOAC 997.11, 18th

Salmonella

Negative

Negative

FDA (BAM) Chapter 5, 8th Ed.

4-product function

1.Bengenin can be used as herbal antitussive expectorant and for treatment of chronic bronchitis.This product has demulcent, sedative and hypnotic and stable effect,
2.Bengenin purpurascens Analgetic weak in PaiTiDing, than general antipyretic analgesics. In the therapeutic doses without breathing inhibition, nor cause gastrointestinal smooth muscle spasm.
3.Chronic persistent pain and viscera of blunt painful effect is good, the sharp pain in acute pain after surgery (e.g., traumatic pain), late-stage cancer pain effect is poorer.
4.The analgesic action, can cause sedative and hypnotic. This product is to clarify the mechanism, and inhibit the reticular activating system structure, block up within the brain dopamine receptor function.

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