Synephrine Hydrochloride CAS No 5985-28-4

1.CAS No.:5985-28-4.
2.Specification: 99%
3.Appearance: White powder
4.MOQ:1KG
5.Sample: Available
6.Certificates: COA, Halal, Kosher, ISO22000, cGMP.

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Product Details

Synephrine Hydrochloride CAS No 5985-28-4


Basic Information

Product Name: Synephrine hydrochloride

Other Name: Benzenemethanol, p-Methylaminoaethanolphenol hydrochlorid

Molecular Weight: 203.67 

Molecular Formula: C9H13NO2·HCl

CAS NO:5985-28-4

Purity:≥99.0%

Appearance: White crystalline powder, soluble in alcohol, sealed at low temperature and protected from light.


Functions

Synephrine HCL is a popular ingredient commonly found in weight loss supplements. Its popularity increased in the United States.

Synephrine has become one of the top ingredients found in dietary supplements.

Derived directly from the fruit of the citrus tree, citrus aurantium, Synephrine HCL is commonly used for weight loss. Synephrine is a stimulant, similar to caffeine, which is claimed to increase energy levels. It is thought to have similar effects in terms of providing an energy boost, suppressing appetite and increasing metabolic rate. Synephrine is one of the adrenergic amines that stimulates beta-3 receptors with minimal impact on the other receptor sites. This helps to increase the metabolic rate without affecting heart rate or blood pressure. Synephrine releases adrenaline and noradrenaline only in the beta-3 receptor sites Stimulation of the beta-3 receptor sites elicits the breakdown of lipolysis (fat).Prevent breast, uterine and colorectal cancer.


Usage: Pharmaceutical Intermediates


Certificate of Analysis

Basic information

Product Name

Synephrine Hydrochloride

Structure

5985-28-4

CAS No.

5985-28-4

Molecular formula

C9H13NO2·HCl

Molecular weight

203.67

EINECS

227-804-6

Batch Number

SH200714

Date of Certificate

April 25th, 2020

Standard Item

Specification

Test Results

Appearance

White Crystalline Powder

Confirm

Identification

A.H-NMR:Comply with the structure

Complies

B.LC-MS:Comply with the structure

Complies

C.The IR spectrum of sample should be identical with that of reference standard;

Complies

D.HPLC-ESI-MS

The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

Complies

Crystallinity

Meets the requirements.

Complies

Loss on drying

≤1.0%

0.85%

Heavy metals

≤10 ppm

<10ppm

Water

≤1.0%

0.1%

Sulphated ash

≤0.5%, determined on 1.0 g.

0.009%

Related substances

Unspecified impurities: for each impurity

≤0.10%

<0.10%

Total Impurity

≤0.5%

0.18%

Mass

203.67±1

Conforms

NMR

Comply with the structure

Conforms

Purity

≥99.0%

99.29%

Assay

99.0%~101.0% (anhydrous substance).

99.63%

Microbiological Analysis

Total plate count

≤1000cfu/g

Complied

Yeast and Moulds

≤100cfu/g

Complied

E. Coli.

Absent

Negative

Salmonella

Absent

Negative

S.aureus

Absent

Negative

Storage

Preserve in well-closed, light-resistant and airtight containers.

Retest date

Two years under conditions list above

Conclusion

Confirmed


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